Jacksonville Jaguars vs. Philadelphia Eagles picks, predictions: Who wins NFL Week 4 game?

Jeremy Cluff, Arizona Republic

September 26, 2022 at 7:40 PM·4 min read

The Jacksonville Jaguars and Philadelphia Eagles play on Sunday in a game on the NFL Week 4 schedule.

Which team will get the victory?

Check out these NFL Week 4 picks and predictions for the game, which can be seen at 10 a.m. MST on CBS.

The Eagles are a 6.5-point favorite in the game.

The Arizona Republic: Eagles 31, Jaguars 21

Jeremy Cluff writes: "The Jaguars have been very impressive so far this season, but the Eagles' defense will be able to slow down Trevor Lawrence and company in Philadelphia."

Draft Kings: Go with the Eagles to cover against Jaguars

It writes: "Philadelphia’s offense is on fire, and the defense is playing with a lot of confidence after two strong showings. Jacksonville will want to win this one for Pederson, but picking against the Eagles right now is not a smart idea."

NFL Week 4 odds:

Fansided: Eagles 34, Jaguars 24

Geoffrey Knox writes: These are the games that a great team is supposed to win. A raucous home crowd will help keep the home team energized. Following an emotional and impressive road win by the Jaguars, asking them to play at that same level in consecutive weeks might be too big of an ask for a young team. We’re taking the Birds. We expect them to improve to 4-0 on the season."

Bookies.com: Take the Jaguars with the points vs. Eagles

Bill Speros writes: "After Sunday of Week 3, the Eagles were the lone 3-0 team in the NFC. We've been flying with the Eagles each week this season and have been rewarded for doing so. The Jaguars showed plenty of fang by zapping the Chargers 38-10 in Week. 3. Philadelphia (-6.5) made easy work of Washington 24-8. The Jaguars have the feel of the 2021 Lions, a team that might not win many games on the field but has all the tools to overachieve against the spread. Detroit was 3-13 overall and 11-6 ATS last season. Look for a similar divergence from the Florida Cats this year. We are likely witnessing a second-year leap from Trevor Lawrence. The line has swelled to Philly -7. A perfect opportunity for Jacksonville to grab a backdoor cover."

More: NFL Week 4 schedule, television information: How to watch Week 4 NFL games

Will Christian Kirk and the Jacksonville Jaguars beat the Philadelphia Eagles in their NFL Week 4 game?

Sports Betting Dime: Jaguars 20.8, Eagles 19.4

The site's formula predicts that the Jaguars will beat the Eagles in the NFL Week 4 game.

FanDuel: Bet the Eagles to cover against Jaguars

Isaiah De Los Santos writes: "This battle may be lopsided, according to the opening betting lines. ESPN's FPI agrees, so it's hard to back the Jaguars here. The Eagles' offense is absolutely clicking to begin the year, and their defense has been equally as great. They just have too much firepower on both sides of the ball for Jacksonville to keep up with."

More: NFL power rankings Week 4: Philadelphia Eagles, Miami Dolphins, Jacksonville Jaguars rise

Betsided: Take the over in Jaguars vs. Eagles game

Josh Yourish writes: "Hurts is taking a step into the MVP conversation and potentially the elite quarterbacks of the league, but I think Trevor Lawrence is not too far behind. Lawrence looked fantastic against the improved Chargers defense and I think he can go punch for punch for Hurts this week. I’ll probably wait to see where the line goes to make my bet on this game but for right now I’ll back both of these quarterbacks and take the over."

ESPN: Eagles have a 66.9% chance to win the game

The site's Football Power Index gives the Jaguars a 32.7% shot at picking up the victory.

More: NFL Week 4 odds: Point spreads, moneylines, over/under for every Week 4 NFL game

Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on Twitter @Jeremy_Cluff.

Support local journalism: Subscribe to azcentral.com today.

This article originally appeared on Arizona Republic: Jacksonville Jaguars vs. Philadelphia Eagles picks NFL Week 4

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